Compositions and methods for cell transformation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514169, 514171, 536 5, A61K 31715

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057958700

ABSTRACT:
The present invention relates to methods and compositions for the transformation of cells. In particular, compositions and methods are disclosed which include combinations of the nucleic acid of interest and polyhydroxylated or polyglycosylated steroid molecules. Most preferably, exogenous or endogenous nucleic acid is contacted with the cell in the presence of a bile acid (e.g., cholic acid) derivatized with an amine-containing side chain.

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