Compositions and methods for angiogenesis-related molecules...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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C536S023100, C536S024300, C536S024330

Reexamination Certificate

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07667028

ABSTRACT:
Short interfering RNA (siRNA) molecules which modulate the expression of an angiogenesis-related gene by RNA interference are described. Short hairpin RNA (shRNA) molecules comprising said siRNA molecules are also described. These molecules can target all, or specific, isoforms of the gene. The use of these molecules and of isoforms of the gene for the treatment and diagnosis of angiogenesis-related disorders is also described.

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