Compositions and methods for administering therapeutically activ

Details Compositions and methods for administering therapeutically activ Compositions and methods for administering therapeutically activ

1988-09-19

1990-11-06

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514165, 514198, 514413, 514419, 514563, 514564, 514567, 514569, 514570, 514629, 514946, A61K 3134, A61K 3160, A61K 3119, A61K 31195

Patent

active

049687166

ABSTRACT:
A composition useful for administering therapeutically active compounds to improve the body absorption and/or retention thereof comprising a composition which includes a therapeutically active compound having a molecular weight below about 5,000 and having an acidic functional group, which is normally eliminated from the body via the renal tubular secretion pathway for organic anions, for example, Vitamin C, and at least one compound selected from the class consisting of L-threonic, L-xylonic and L-lyxonic acids, and the edible salts, aldono-lactones and aldono-lactides thereof.
A method for establishing and maintaining body levels of a therapeutically active compound which includes the step of administering a therapeutically effective dose of this composition.

REFERENCES:
patent: 3459863 (1969-08-01), Apelian et al.
patent: 3781423 (1973-12-01), Aoka et al.
Lewin-Vitamin C, Its Molecular Biology and Medical Potentials-Academic Press (1976).

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