Compositions and methods for activating genes of interest

Details Compositions and methods for activating genes of interest Compositions and methods for activating genes of interest

2006-02-27

2008-10-21

McGarry, Sean R (Department: 1635)

Chemistry: molecular biology and microbiology

Vector, per se

C435S006120, C435S069100, C536S023100, C536S024100, C536S024500

Reexamination Certificate

active

07439059

ABSTRACT:
Compositions and methods for activating genes of interest are provided. The compositions comprise a masked targeted expression cassette which expresses a gene product only in the presence of a target molecule. The cassettes are useful for the treatment of disease and for preventing the proliferation of neoplastic cells.

REFERENCES:
patent: WO 92/13070 (1992-08-01), None
Hirashima et al. PNAS vol. 83:7726-7730, Oct. 1986.

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