Drug – bio-affecting and body treating compositions – Lymphokine
Reexamination Certificate
2004-05-25
2008-03-25
Kemmerer, Elizabeth C. (Department: 1647)
Drug, bio-affecting and body treating compositions
Lymphokine
C424S085200, C435S069500, C435S069520, C435S069700, C435S071100, C530S351000
Reexamination Certificate
active
07347995
ABSTRACT:
Disclosed herein are therapeutic compositions containing agents that modulate the immune response in a patient.
REFERENCES:
patent: 5116964 (1992-05-01), Capon et al.
patent: 5552303 (1996-09-01), Grabstein et al.
patent: 5574138 (1996-11-01), Grabstein et al.
patent: 5707616 (1998-01-01), Grabstein et al.
patent: 5747024 (1998-05-01), Grabstein et al.
patent: 5892001 (1999-04-01), Grabstein et al.
patent: 19823351 (1998-12-01), None
patent: WO 88/07089 (1988-09-01), None
patent: WO 93/08207 (1993-04-01), None
patent: WO 93/19770 (1993-10-01), None
patent: WO 94/04180 (1994-03-01), None
patent: WO 94/04570 (1994-03-01), None
patent: WO 94/17773 (1994-08-01), None
patent: WO 95/06480 (1995-03-01), None
patent: WO 95/06481 (1995-03-01), None
patent: WO 95/06666 (1995-03-01), None
patent: WO 95/27722 (1995-10-01), None
patent: WO 95/28957 (1995-11-01), None
patent: WO 96/16665 (1996-06-01), None
patent: WO 96/23071 (1996-08-01), None
patent: WO 96/26274 (1996-08-01), None
patent: WO 9626274 (1996-08-01), None
patent: WO 96/40246 (1996-12-01), None
patent: WO 97/17446 (1997-05-01), None
patent: WO 97/20063 (1997-06-01), None
patent: WO 97/22256 (1997-06-01), None
patent: WO 97/26000 (1997-07-01), None
patent: WO 97/34633 (1997-09-01), None
patent: WO 9741232 (1997-11-01), None
patent: WO 98/01145 (1998-01-01), None
patent: WO 98/52606 (1998-11-01), None
patent: WO 98/56417 (1998-12-01), None
patent: WO 98/58672 (1998-12-01), None
patent: WO 99/00143 (1999-01-01), None
patent: WO 99/12566 (1999-03-01), None
Mijares et al, Molecular Pharmacology, 2000, vol. 58, pp. 373-379.
Boulougouris et al, The Journal of Immunology, 1998. vol. 161, pp. 3919-3924.
Lin, et al.The Role of Shared Receptor Motifs and Common Stat Proteins in the Generation of Cytokine Pleiotropy and Redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.Immunity, 2:331-339 (Apr. 1995).
Morrison, et al.Structural Determinants of Human IgG Function. The Immunologist 2(4):119-124 (1994).
Brekke, et al.Structure-Function Relationships of Human IgG.The Immunologist 2(4):125-130 (1994).
Pettit, et al.Structure-Function Studies of Interleukin 15 using Site-specific Mutagenesis, Polyethylene Glycol Conjugation, and Homology Modeling. The Journal of Biological Chemistry 272(4): 2312-2318 (1997).
Stevens, et al.Interleukin-15 signal, T84 colonic epithelial cells in the absence of the interleukin-2 receptor β-chain. Am. J. Physiol. 272:G1-G8 (1997).
Armitage, et al.IL-15 Has Stimulatory Activity for the Induction of B Cell Proliferation and Differentiation. Journal of Immunology 154:483-490 (1995).
Chae, et al.Distribution of IL-15 Receptor α-Chains on Human Peripheral Blood Mononuclear Cells and Effect of Immunosuppressive Drugs on Receptor Expression. Journal of Immunology 157:2813-2819 (1996).
Moreland, et al.Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor(p75)-Fc Fusion Protein. N. Engl. J. Med 337(3):141-147 (1997).
Elliott, et al.Repeated therapy with monoclonal antibody to tumor necrosis factor α(cA2)in patients with rheumatoid arthritis. Lancet 344(8930):1125-1127 (1994).
Elliott, et al.Randomized double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor α(cA2)versus placebo in rheumatoid arthritis. Lancet 344(8930):1105-1110 (1994).
Williams, et al.Successful therapy of collagen-induced arthritis with TNF receptor-IfG fusion protein and combination with anti-CD4. Immunology 84(3): 433-439 (1995).
Wooley, et al.Influence of a Recombinant Human Soluble Tumor Necrosis Factor Receptor FC Fusion Protein on Type II Collagen-Induced Arthritis in Mice. Journal of Immunology 151(11):6442-6607 (1993).
Vey, et al.IFN-γ and 1,25(OH)2D3Induce on THP-1 Cells Distinct Patterns of Cell Surface Antigen Expression, Cytokine Production, and Responsiveness to Contact with Activated T Cells. Journal of Immunology 149(6):2040-2046 (1992).
Courtenay, et al.Immunisation against heterologous type II collagen induces arthritis in mice.Nature 283(5748): 666-668 (1980).
Burger, et al.Imbalance between interstitial collagenase and tissue inhibitor of metalloproteinases I in synociocytes and fibroblasts upon direct contact with stimulated T Lymphocytes. Arthritis & Rheumatism 41(10):1748-1759 (1998).
Kim, et al.Targeting the IL-15 Receptor with an Antagonist IL-15 Mutant/Fcγ2a Protein Blocks Delayed-Type Hypersensitivity. Journal of Immunology 160:5742-5748 (1998).
Li, et al.Induction of Allograft Tolerance in the Absence of Fas-Mediated Apoptosis.Journal of Immunology 163:2500-2507 (1999).
Kim, et al.Targeting the IL-15 Receptor with an Antagonist IL-15/Fcγ2a Protein BlocksDTH and Enhances the Acceptance of Islet Allografts. 17thASTP (Physicist) Annual Meeting, Chicago, IL May 9-13, 1998 (p. 713).
Kirk, et al.Treatment of humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates.Nature Medicine 5(6):686-693 (1999).
Nickerson, et al.Prolonged islet allograft acceptance in the absensce of interleukin 4 expression.Transplant Immunology 4:81-85 (1996).
Lakkis, et al.Interleukin 4 receptor targeted cytotoxicity: genetic construction and in vivo immunosuppressive activity of a diphtheria toxin-related murine interleukin 4 fusion protein. Eur. J. Immunol. 21:2253-2258 (1991).
Li, et al.Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance.Nature Medicine 5(11):1298-1302 (1999).
Agostini et al.,Blood, v93 (No. 4), pp. 1277-1286 (Feb. 1999).
Ferrari-Lacraz et al.,Jrl. Of Immuno., v167 (No. 6), pp. 3478-3485 (Se. 2001).
Kim et al.,Jrl. Of Immuno.,v160 (No. 12), pp. 5742-5748 (Je. 1998).
Kim et al.,Transplantation Proceedings, v30 (No. 8), pp. 4031-4036 (1998).
Ferrari-Lacraz Sylvie
Kim Yon Su
Maslinski Wlodzimierz
Strom Terry B.
Zheng Xin Xiao
Beth Israel Deaconess Medical Center Inc.
Hamud Fozia
Kemmerer Elizabeth C.
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