Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1989-01-27
1991-07-16
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
424435, 424443, 514900, 514902, A61K 716, A61K 906, A61K 970, A61L 1503
Patent
active
050323849
ABSTRACT:
Synergistic compositions comprising an antioxidant and an arylpropionic, non-steroidal anti-imflammatory drug used to treat certain diseases are disclosed. The compositions inhibit production of arachidonic acid cascade end-products which have been implicated as causes of tissue-destruction in periodontal disease. The compositions are administered in combination with a carrier, which may be a mucosal-tenacious polymer selected from the groups of semi-solid pastes, gels, ointments, liquids or films.
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Alfano Michael C.
Sena Frank J.
Yeh Kuo-Chen
Block Drug Company Inc.
Rose Shep K.
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