Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1986-08-15
1989-02-28
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 54, 514 56, 514822, A61K 3700, A61K 31725
Patent
active
048085707
ABSTRACT:
The healing of wounds is promoted by contacting the wound surfaces with a suspension of collagen and a glycosaminoglycan that is chemotactic for fibroblasts and/or endothelial cells. Typical glycosaminoglycans that exhibit the desired chemotaxis are heparin, heparan sulfate, and alginate. Two or more glycosaminoglycans can be present in the suspensions. Collagen is present in the suspension in the order of 7-10 mg/ml; while the glycosaminoglycan is present in such lower concentrations, e.g. 250-350 .mu./ml. Application of the collagen/glycosaminoglycan suspension to open wounds greatly increases the rate of healing.
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Rollins John W.
University of California
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