Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-08-11
1991-07-09
Shah:, Mukund
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142288, 514256, 514275, 514356, 514374, 514376, 514377, 514385, 514392, 514423, 514470, 514652, 514772, 514788, 514946, 514947, A61K 31415, A61K 3142, A61K 31495, A61K 31535
Patent
active
050306294
ABSTRACT:
A method and compositions for enhancing absorption of topically administered physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or formulation for local or systemic use, comprising a therapeutically effective amount of a pharmaceutically active agent and a non-toxic, effective amount of penetration enhancing agent of the formula I: ##STR1## wherein R is a saturated or unsaturated, straight or branched, cyclic or acyclic hydrocarbon group with from 1 to 19 carbon atoms, alkoxyalkyl, haloalkyl, specifically trifluoromethyl, alkoxy, amino, alkylamino and acylamino; R' and R" are hydrogen, alkyl, trifluoromethyl, alkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, carboxy, carbalkoxy, hydroxyalkyl or lower alkyl ester thereof; X is O or NR.sub.1 wherein R.sub.1 is hydrogen, alkyl, alkenyl, alkoxyalkyl, carbalkoxyalkyl, aminoalkyl, alkyl- and acylaminoalkyl, hydroxyalkyl or hydroxyalkyloxyalkyl and lower alkyl ester thereof; and n is 2 or 3 are disclosed.
REFERENCES:
patent: 4876249 (1989-10-01), Rajadhyaksha
patent: 4960771 (1990-10-01), Rajadhyaksha
Datlow Philip I.
Shah: Mukund
LandOfFree
Compositions and method comprising heterocyclic compounds contai does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and method comprising heterocyclic compounds contai, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and method comprising heterocyclic compounds contai will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-618340