Compositions

Details Compositions Compositions

1991-05-16

1992-05-12

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Hydroxy carboxylic acid or derivative thereof

424 49, A61K 716, A61K 724

Patent

active

051126001

ABSTRACT:
An anti-caries composition has a source of hydrogen citrate ions, preferably an alkali metal hydrogen citrate salt, an oxalate salt and an orally acceptable excipient, and optionally further comprises an ionic fluorine-containing compound. The composition may be in the form of dentifrice when silica is the preferred abrasive, or a mouthwash.

REFERENCES:
patent: 4057621 (1977-11-01), Pashley et al.
patent: 4645662 (1987-02-01), Nakashima et al.
patent: 5026539 (1991-06-01), Jackson et al.
Duke et al. CA. 109:215748e (1988) of Caries Res. 22(6):350-2 (1988).
Duke et al. CA. 105:120543n (1986) of EP 188 313 23 Jul. 1986 14 pp.
Pashley et al. CA. 102:31929p (1985) of J. Peurdent, 55(9):522-5 (1984).
Pashley et al. CA. 88:55104j (1978) of U.S. 4,057,621 8 Nov. 77.
Lion Corp. CA. 102:172445g (1985) of JPN 6004117 10 Jan. 1985.
Schott et al. CA. 101:157538h (1984) of J. Pharm. Sci. 73(6), 793-9 (1984).
Just et al. CA. 88:8865y (1978) of Ger. Ofc. 2,615,698 20 Oct. 1977.

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