Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1989-07-21
1990-05-29
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
514168, 552653, A01N 4500, A61K 3159
Patent
active
049296108
ABSTRACT:
Novel combination preparations containing 1.alpha.,25-dihydroxy vitamin D.sub.3 or 1.alpha.-hydroxy vitamin D.sub.3 and 1.alpha.,24,25(or 1.alpha.,25,26)-trihydroxy vitamin D.sub.3 are described. These preparations are useful in the treatment of various disorders which are characterized by disturbances of the calcium and phosphate metabolism such as osteoporosis and can also be used in animal nutrition.
REFERENCES:
patent: 4225596 (1980-09-01), DeLuca
patent: 4495181 (1985-01-01), Norman et al.
patent: 4617297 (1986-10-01), Boris et al.
Endocrinology 117 (5) 2203-2210, 1985.
Kidney Internatl. 26 (4) 490, 1984.
J. Nutr. 113 (12) 2505-15, 1983.
Clinical Science (1983) 65, 429-436.
Proceedings of the Sixth Workshop on Vitamin D, Merano, Italy, Mar. 1985, Norman et al. (ed.), Berlin/New York, 1985.
Biochem. Biophys. Res. Comm. 126 (1) 490-501, 1985.
Meier Werner
Rambeck Walter A.
Weiser Harald
Zucker Hermann
Gould George M.
Hoffmann-La Roche Inc.
Isgro William G.
Lee Mary C.
Leon Bernard S.
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