Composition useful for the fabrication of vaccines

Details Composition useful for the fabrication of vaccines Composition useful for the fabrication of vaccines

1991-02-28

1994-06-28

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 858, 424 86, A61K 3912, A61K 3900, A61K 3942

Patent

active

053245130

ABSTRACT:
The invention concerns a composition useful for the manufacture of vaccines containing particles having the immunogenic properties characteristic of the antigen HBsAg, these particles being more particularly characterized by the fact that the said particles equally contain a receptor for polymerized human albumin. They are obtained by transformation of human or animal cells by a vector containing a DNA sequence coding for the S and pre-S regions of a genome of viral hepatitis B, this DNA sequence being placed under the direct control of a promoter permitting the effective transcription of the said sequence in the human or animal cells transformable by the said vector.

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