Composition to treat ear disorders

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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Details

514171, 514254, A61K 31495, A61K 3156

Patent

active

060934174

ABSTRACT:
A topical ear composition that uses penetration enhancers to diffuse the therapeutic agents through the tympanic membrane into the middle and inner ear for the purpose of reducing the inflammation of ear tissues, providing pain relief, and introducing agents with antimicrobial activity to combat infection. The composition reduces swelling of the lining membranes of the middle and inner ear, prevent the destructive effects of inflamation, inhibit the production of prostaglandins, reduce symptoms of tinnitus and vertigo, improve and prevent paralysis of the facial nerve, relieve labyrinthitis, and prevent hearing loss.

REFERENCES:
patent: 3946123 (1976-03-01), Hanna
patent: 4025620 (1977-05-01), Beyer et al.
patent: 4628063 (1986-12-01), Haines et al.
patent: 4851442 (1989-07-01), Watson
patent: 4914131 (1990-04-01), Haines et al.
patent: 4933184 (1990-06-01), Tsuk
patent: 4954486 (1990-09-01), Guth
patent: 4956391 (1990-09-01), Sapse
patent: 5061729 (1991-10-01), Kineses et al.
patent: 5064858 (1991-11-01), Sapse
patent: 5229130 (1993-07-01), Sharma et al.
patent: 5238933 (1993-08-01), Catz et al.
patent: 5447930 (1995-09-01), Mayak
patent: 5462749 (1995-10-01), Rencher
patent: 5827529 (1998-10-01), Ono et al.
patent: 5837289 (1998-11-01), Grasela et al.
patent: 5843930 (1998-12-01), Purwar et al.
Gabor et al., Chemical Abstracts, vol. 117, #163362, 1993.
Sakamoto, World Patents Index, vol. 78, #84512, 1978.
Van Lengerich et al., Chemical Abstracts, vol. 129, #8597, May 1998.
Shambaugm GE Jr, Zinc: The Neglected Nutrient Am J Otol 1989 Mar; 10(2):156-60.
Steel KP, A New Era in the Genetics of Deafness Lancet 1998;339:1545-47.
Prasher D, New Strategies for Prevention and Treatment of Noise-Induced Hearing Loss Lancet Oct. 17, 1998 p 1240 (1).
Thomas DW, An Earful of Auditory Advice Dogworld Nov. 1996; 38-9.
Townsend GC, Scheld WM, Adjunctive Corticosteroids for Adult Bacterial Meningitis Infect Med 1995; 12 (12);701-10.
Windler JA, Nasal Polyposis: Rationale for Treatment with Medscape Respiratory Care 1998; 2(1).
Borowitz SM, Topical Corticosteroid Preparations Pediatric Pharmacotherapy 1996;2(1).
Poole MD Declining Antibiotic Effectiveness in Otitis Media A Convergence of Data. Ear Nose & Throat Journal 1998, 77(6);444-47.
Estrada B, Infectious Causes of Hearing Loss Beyond Otitis Media Infect Med 14 (3):239-244, 1997.
Osborne DW, Henke JJ, Skin Penetration Enhancers Cited in the Technical Literature Pharmaceutical Technology Nov. 1997, p58-86.
Modeland V. When Bells Are Ringing (But There Aren't Any Bells).FDA Consumer vol. 13, No. 3.
Hulshof JH, Vermen P, The Value of Tocanaide in the Treatment of Tinnitus, Arch Otorhinolaryngol 1985; 241 (3):279-83.
Pulec JL, Hodell SF, Anthony PF, Tinnitus: Diagnosis and Treatment Ann Otol Rhinol Laryngol 1978 Nov.-Dec.;87(6Pt1):821-33.
Von Wedel H, Von Wedel UC, Zonowka P, Tinnitus Diagnosis and Therapy in the Aged Acta Otolaryngol Suppl(Stockl) 1990;476:195-201.
Shea JJ, Medical Treatment Of Tinnitus Acta Otorhinolaryngol Belg 1985; 39(3):613-9.
Crinnion CL, McCarr GM, Misoprostol for Tinnitus Ann Pharmacother 1995 Jul.-Aug.; 29(7):782-4.
Denk DM, et al, Caroverine In Tinnitus Treatment Acta Otolaryngol (Stock h) 1997 Nov.;117(6):825-30.
Petrus EJ et al Randomized, Double-Masked, Placebo-Controlled Clinical Study of the Effectiveness of Zinc Acetate Lozengos On Common Cold Symptoms in Allergy-Tested Subjects. Current Therapeutic Research 1998;59/9;595-607.
Bylander-Groth A, Stenstrom C, Eustachian Tube Function and OtitisMedia in Children. Ear, Nose & Throat Journal 1998;77(9);762-69.

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