Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules
Patent
1996-09-03
1999-02-02
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Capsules
424439, 424455, 424464, 424520, 426285, 426521, 426524, 426641, 426646, 514879, A61K 920, A61K 948
Patent
active
058661603
DESCRIPTION:
BRIEF SUMMARY
This application is a 371 of PCT/CN95/00001 filed Jan. 4, 1995.
FIELD OF THE INVENTION
The present invention relates to a composition of soft-shelled turtle and tortoise (TT Composition) and the preparative method thereof. It also relates to the use of the composition which is beneficial to human beings.
BACKGROUND OF THE INVENTION
In modern society, the rhythm of daily life is quicker than before. People are physically injured and mentally affected owing to the heavy work and labor which causes hypoimmunity of the organism, disorders of physiological regulation systems, fatigue and a variety of diseases. Moreover, the proportion of the aged population in society is increasing. The health care and prolonging of the life of the aged has become a prominent problem. Therefore, it is urgent to find a pharmaceutical product which is beneficial to the human body and is easy to use.
In the literature of Chinese traditional medicine, soft-shelled turtle and tortoise were recorded as effective medicinal components. However, for a long time, both of them were used only by a small number of patients or as cooked food in a restaurant. They were processed mainly in boiling water with some seasonings or steamed due to limited cookery. Their effectiveness as medicaments was not fully utilized and their application scope was greatly limited. Recently oral liquor of soft-shelled turtle and capsule of tortoise as well as food containing turtle have been developed (See Japanese Patent Publication Sho59-5020). Among these products, the effective components in the oral liquor are extracted by means of enzymatic hydrolysis, but it is not possible to micro-pulverize the mineral elements and proteins in the available turtle shell which is finally littered. As for the capsule, there is no best way to avoid complete carbonification of proteins of tortoise during the processing by the process of Chinese traditional medicine. A certain amount of nourishing components is lost. Japanese Patent Publication Sho57-1980 has disclosed a method for manufacturing turtle powder by means of pulverization under the frozen condition with the aid of liquid nitrogen, and Japanese Patent Publication Sho59-5020 has disclosed a series of nourishment-enriched foods containing turtle powder as an active principle in the form of a capsule, a granule and a tablet. However, only soft-shelled turtles are involved in these products. Therefore, there is a need to develop new products which are beneficial to humans.
SUMMARY OF THE INVENTION
The object of the present invention is to develop a composition of soft-shelled turtle and tortoise without the loss of nourishing components so that the beneficial actions of turtle and tortoise to humans are fully combined to achieve better results.
After an extensive and deep study, the inventor comes to the following invention:
The whole turtle and tortoise are pulverized under the frozen condition with the aid of liquid nitrogen. A variety of dosage forms, such as capsules etc., are made of the turtle-tortoise powder according to the conventional manner and then sterilized with irradiation.
It is found that the composition of turtle and tortoise shows a good physiological activity with a broad therapeutic spectrum, such as strengthening human resistance to diseases, regulating the central system, cardiovascular system and endocrine system, anti-senility, inhibiting action on a tumor etc.
DETAILED DESCRIPTION OF THE INVENTION
The first object of the invention relates to a TT composition, comprising 5-95% turtle by weight and 95-5% tortoise by weight.
The second object of the invention relates to a method for preparing a composition of soft-shelled turtle and tortoise, characterized in that the living turtle and tortoise are separately granulated under the frozen condition (low temperature) with the aid of liquid nitrogen; the resulted granules are dehydrated by lyophilization or other dry manner; after drying, the soft-shelled turtle granule and tortoise granule are mixed and pulverized under liquid nitrogen
REFERENCES:
patent: 4426398 (1984-01-01), Kokura et al.
Webster's New World Dictionary, Neufeldt, et al., pp. 1412 and 1443, Jan. 1988.
Sheng Jin-rong, et al. "The Pharmacological Research of Sea Turtle Ointment". Zhong Cheng Yao Yanjiu, 1981. No. 5, p. 42.
Hong Mengxue
Zhong Shanshan
Hainan Life-Nourishing Pharmacy Co.
Page Thurman K.
Spear James M.
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