Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1993-03-22
1994-05-24
Hollinden, Gary E.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
436173, 436806, 1286534, 324307, 324308, 514315, 514424, 514836, A61B 5055, A61K 31445, A61K 3140, G01V 300
Patent
active
053146816
ABSTRACT:
The invention relates to a modification of electron spin resonance enhanced magnetic resonance imaging (ESREMRI) in which two magnetically responsive materials (contrast agents) are introduced into the sample being investigated, one contrast agent serving as an ESREMRI free induction decay signal enhancing agent and the other as enhancement suppressing agent. In this way, image contrast may be enhanced further for regions in which the suppressing agent distributes poorly or not at all or which the suppressing agent reaches at a later time than the enhancing agent.
REFERENCES:
patent: 4615879 (1986-10-01), Runge et al.
patent: 4637929 (1987-01-01), Quay
patent: 4639365 (1987-01-01), Sherry
patent: 4647447 (1987-03-01), Gries et al.
patent: 4675173 (1987-06-01), Widder
patent: 4687659 (1987-08-01), Quay
patent: 4730066 (1988-03-01), White
patent: 4746507 (1988-05-01), Quag
patent: 4863715 (1989-09-01), Jacobsen et al.
patent: 4863717 (1989-09-01), Keana
patent: 4891593 (1990-01-01), Lurie et al.
Lurie, D. J. et al. J. Magnetic Resonance 76:366-70 (1988).
Sosnovsky, G. et al. Z. Naturforsch 41B:1170-7 (1986).
Villringer, A. et al. Magnetic Resonance in Medicine 6:164-74 (1988).
Bacic, G. et al. Magnetic Resonance in Medicine 8:209-18 (1988).
Alcock et al., Tetrahedron, 33, 2969-2980, 1977.
Golding et al., Synthesis, 7, 463-463, 1975.
Eriksson et al., J. Pharm. Sci., 77, 2, 97-103, 1988.
Hall et al., Magnetic Resonance in Medicine, 7, 248-252, 1988.
Golman Klaes
Klaveness Jo
Leunbach Ib
Hollinden Gary E.
Nycomed Innovation AB
LandOfFree
Composition of positive and negative contrast agents for electro does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Composition of positive and negative contrast agents for electro, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition of positive and negative contrast agents for electro will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1971317