Composition of matter comprising an imprinted matrix exhibiting

Details Composition of matter comprising an imprinted matrix exhibiting Composition of matter comprising an imprinted matrix exhibiting

1991-02-01

1994-05-10

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 2, 435 4, 435 34, 435 721, 435 723, 4352402, 4352351, 530350, 530395, A01N 102, C12Q 170, C12Q 104, C12N 500

Patent

active

053106482

ABSTRACT:
The invention provides an imprinted matrix which exhibits selective binding interactions through metal chelates with a predetermined molecule or biological particle. Also provided is a preformed, fluid-imprinted matrix having sufficient rigidity to maintain selective binding interaction with a predetermined molecule or biological particle through interactive moieties. Methods for producing such matrices are additionally provided.

REFERENCES:
Dodrer, N. and Regen, S., "Polymerized Liposomes Designed to Probe and Exploit Ligand-Receptor Recognition at the Supramolecular Level", J. Am. Chem. Soc. 112 2829-2830 (1990).
Day, D. et al., "Polymerization of Mono- and Bi-functional Diacetylene Derivatives in Monolayers at the Gas-Water Interface", Israel Journal of Chemistry: 18 325-329 (1979).
Fuhrhop, J. and Mathieu, J., "Routes to Functional Vesicle Membranes without Proteins", Angew. Chem. Int. Ed. Engl.:23 100-112 (1984).
Porath, Jerker et al., "Metal chelate affinity chromatography, a new approach to protein fractionation", Nature 258:598-599 (1975).
Gunter Wulff, "Molecular Recognition in Polymers Prepared by Imprinting with Templates", ACS Symp. Ser. 308, 186-230 (1986).
Ekberg, B. and Mosbach, K., "Molecular imprinting: a technique for producing specific separation materials", Tibtech 7:92-96 (1989).

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