Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1981-12-07
1984-02-07
Kepplinger, Esther M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
435172, 435942, 435256, 435317, C12P 2100, C12N 1500, C12N 118, C12R 1865
Patent
active
044304285
ABSTRACT:
A process for expression of a gene, foreign to the host organism, coding for a protein in a suitable vehicle which comprises taking said gene and fusing it in the correct orientation relative to a transcriptional initiation region present in said vehicle, and inserting said vehicle into a eukaryotic host. Via the subject process, the gene for chicken ovalbumin is expressed in the yeast Saccharomyces cerevisiae. Chicken ovalbumin can be used in the food, i.e., baking, industry and also as a protein supplement for animals.
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Struhl et al., PNAS, 76(3), 1035-1039, (Mar. 1979).
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Lemke, Viruses and Plasmids in Fungi, Marcel Dekker, Inc., New York, 588-589, (1979).
McReynolds et al., Chemical Abstracts, 88:117644w, 258 (1978).
Itakura, K., Hirose, T., Crea, R., Riggs, A. D., Heyneker, H. L., Bolivar, F. and Boyer, H. W., (1977), Science 198: 1056-1063.
Fraser, T. H. and Bruce, Barbara J., Proc. Natl. Acad. Sci., (1978), 75: 5936-5940.
Bruce Barbara J.
Fraser Thomas H.
Kepplinger Esther M.
Saliwanchik Roman
The Upjohn Company
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