Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using actinomycetales
Patent
1981-09-21
1984-01-24
Goldberg, Jerome D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Using actinomycetales
424122, C12P 106, A61K 3500
Patent
active
044277768
ABSTRACT:
Novel antibiotic U-64,815 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Streptomyces microspinus, NRRL 12524. This antibiotic is active against various Gram-positive bacteria, for example, Staphylococcus aureus. It is also active against Haemophilus influenzae. Thus, antibiotic U-64,815 can be used in various environments to eradicate or control such bacteria.
REFERENCES:
Mallams, A. K. et al., J. Am. Chem. Soc. 103, 3938, 3940, (1981).
Kobinata, K., et al., J. Antib. 33, 244, (1980).
Isono, K. et al., J. Antib. 33, 772, (1980).
Tomita, F. et al., J. Antib. 33, 668, (1980).
Tamaoki, T. et al., J. Antib. 33, 946, (1980).
Coats John H.
Greenfield John C.
Snyder William C.
Whaley Howard A.
Goldberg Jerome D.
Saliwanchik Roman
The Upjohn Company
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