Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1984-05-25
1988-01-12
Shapiro, Lionel M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530363, 424 85, 424 87, 424101, 514 2, 514 6, C07G 700, A61K 3510, A61K 3900
Patent
active
047192909
ABSTRACT:
An intravenous immune globulin preparation having at least 99% pure globulin protein and an anticomplement activity of less than 0.10 C'50 units/mg IgG prepared by: precipitating impurities from Cohn Fraction II in an aqueous-alcohol medium at defined temperature and pH, removing the precipitated impurities, stabilizing the diluted solution with albumin, concentrating the solution and removing the alcohol therefrom. Also prepared by this method, an intravenous, hyperimmune globulin preparation having increased antibody titers to sixteen serospecific strains of Pseudomonas aeruginosa.
REFERENCES:
patent: 2520076 (1950-08-01), Williams et al.
patent: 3903262 (1975-09-01), Pappenhagen
patent: 4021540 (1977-05-01), Pollack et al.
patent: 4124576 (1978-11-01), Coval
patent: 4126605 (1978-11-01), Schneider et al.
patent: 4168303 (1979-09-01), Nishida et al.
patent: 4379086 (1983-04-01), Kimura et al.
patent: 4396608 (1983-08-01), Tenold
patent: 4515776 (1985-05-01), Taniguchi et al.
Smyth, Jr. et al., Industrial Hygiene and Toxicology 2nd Ed. "The Toxicology of the Polyethylene Glycols", pp. 7-12, 1950.
Miler et al., J. Med. Microbiol., vol. 10, pp. 19-27, 1977.
Curry Willie M.
Farb David L.
Armour Pharmaceutical Corporation
Shapiro Lionel M.
Teskin Robin Lyn
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