Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1990-12-21
1992-01-28
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
530380, 530393, A61K 3514, A61K 3704, A61K 3762
Patent
active
050842730
ABSTRACT:
An anticoagulant containing as active ingredients protein C or activated protein C and heparin has a high anticoagulant activity which cannot be obtained with activated protein C or heparin alone. The activity of the anticoagulant is further increased by addition of AT III.
REFERENCES:
patent: 4604285 (1986-08-01), Smith et al.
McLean, Am. J. of Physiol., vol. 41 (1916) p. 250.
Suzuki et al., J.B.C., vol. 258 (1983) p. 1914.
Miller-Anderson et al., Thrombosis Research (1974), vol. 5, pp. 439-452.
Hoechst Japan Limited
Koh Choon P.
Schain Howard E.
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