Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1998-05-13
1999-11-16
Weddington, Kevin E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514547, 514548, 514549, 514557, A61K 3122, A61K 31225, A61K 3119
Patent
active
059859237
DESCRIPTION:
BRIEF SUMMARY
FIELD OF THE INVENTION
The present invention relates to a composition for the treatment of poultry litter, as well as to a process for the use of this composition, so as to reduce the negative effects of coccidiosis in poultry.
BACKGROUND OF THE INVENTION
Coccidiosis is an illness particularly of poultry due to the infection arising from one or several species of coccidiae or protozoa of large size of the sporozoa type. These protozoa, frequent in poultry raising, are ingested by animals in the form of sporulated oocyst. They thus undergo in the digestive tract of animals a cycle of development and multiplication such that, starting from several sporulated oocysts, there are excreted in fecal material millions of non-sporulated oocysts. The non-sporulated oocysts, which are not infectious, are transformed during their stay in fecal material after excretion, and hence in the litter, into sporulated infectious oocysts. But only a portion of the non-sporulated oocysts are transformed into sporulated oocysts; however, the degree of sporulation depends on the composition of the fecal materials: moisture content, oxygen content, pH, etc. If sporulation is intense, the reinfected animals will perish or will experience very reduced growth and production. If sporulation is moderate, the animals will suffer only a slight infection and thus are immunized.
The object of the present invention therefore is to provide a composition adapted to be incorporated in poultry litter, whose action is based on the reduction of sporulation of the oocysts in said litter and permits practically preventing the pathogenic reinfection of the poultry.
There are already known from GB-A-2 108 389 disinfectant compounds for the treatment of litter which contain as a biocidal agent an alkyl benzene sulfonic acid dissolved in an oily hydrophobic base. Such compositions are adapted to act only on the litter itself, and the disinfectant agent that they contain can be harmful to the animals that ingest it.
SUMMARY OF THE INVENTION
However, the present inventor has shown that the incorporation in litter of at least one suitable edible surfactant emulsifier permits obtaining in an altogether unforeseeable manner the results sought by the present invention to reduce significantly the negative effects of coccidiosis in poultry, more particularly by decreasing the sporulation of the oocysts which gives rise to serious lesions due to infected litter.
DETAILED DESCRIPTION OF THE INVENTION
Thus, the composition for the treatment of poultry litter according to the present invention and which achieves the above object, comprises at least one edible surface active emulsifying agent.
The emulsifying agents can be present in the form of water-soluble powder or in liquid form, containing 10 to 100% of said agents; in both cases, the powder or the liquid will be placed in aqueous solution before use. As a support for the powder, can be used for example dextrose, whilst the liquid form is for example in water or propylene-glycol.
The emulsifier or emulgator can be selected preferably from among those which are tolerated by the biological systems and which are mostly hydrophilic in nature, for example esters, polyglycerol esters, and sorbitol esters of fatty acids, such as fatty acid ethoxylates in the form of mono-, di- and triesters of oleic acid, ethoxylates of mono-, di- and triglycerides, ethoxylates of mono- or diesters of sorbitol and fatty acids such as oleic acid or ricinoleic acid, obtained from fatty acids of tallow, soy oil, rape seed oil, castor oil or linseed oil, or coconut oil; and ethoxylated alcohols; etc., the ethoxylates obtained from castor oil being more particularly preferred.
The treatment of litter by the composition according to the invention can take place by a simple spraying on the litter of the liquid composition, in the amount of 20 to 100 ml per m.sup.2 of litter, using one or the other of the mentioned forms after 4 to 5 fold dilution. More particularly, the edible surfactant agents are incorporated in the litter in an
REFERENCES:
patent: 5208257 (1993-05-01), Kabara
patent: 5280042 (1994-01-01), Lopes
patent: 5558889 (1996-09-01), Rossi
patent: 5565211 (1996-10-01), Rossi
Crina S.A.
Weddington Kevin E.
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