Drug – bio-affecting and body treating compositions – Dentifrices – Ferment containing
Patent
1997-09-08
1999-06-01
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
Ferment containing
424 58, 4241951, 514690, A61K 716, A61K 726, A61K 3578, A61K 3843
Patent
active
059086130
ABSTRACT:
The present invention is a compound and method for treating and preventing periodontal disease. The compound contains a gum tissue regeneration agent, such as coenzyme Q.sub.10, and a antimicrobial agent, such as melaleuca alternifolia extract oil, mixed into a solution medium. The compound is applied to the bristles of a brush. The brush then is used to introduce the compound into any pockets that may exist between and around the teeth and gums because of periodontal disease. Once introduced into pockets between the teeth and gums, the compound has a dual effect. First, the antimicrobial agent kills any bacteria in the pockets and prevents the growth of new bacteria in the pockets. Second, the gum tissue regeneration agent promotes growth of the gums against the teeth. As a result, the size of the pockets is reduced over time until the pockets are no longer abnormal and the damage from past periodontal disease is at least partially repaired.
REFERENCES:
patent: 4654373 (1987-03-01), Bertelli
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patent: 5378461 (1995-01-01), Neigut
patent: 5472684 (1995-12-01), Nabi et al.
Hankioka et al Molecular Aspects of Medicine (1994) 15/Suppl S-241-S243 1994 Topical Application of Coenzyme Q10 to The Periodontal Pocket.
Shizukushi et al Biomed. Res (4)(1): 33-40 Effect of Coenzyme Q10 on Experimental Periodontitis in Dogs, 1983.
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