Composition for the preparation of dosage-form active vitamins D

Details Composition for the preparation of dosage-form active vitamins D Composition for the preparation of dosage-form active vitamins D

1993-01-13

1993-11-02

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

514788, 552653, A61K 31595, A61K 4700, C07J17200

Patent

active

052583759

ABSTRACT:
Compositions suitable for use in the preparation of dosage-form active vitamins D.sub.3 are disclosed. Each composition comprises an active vitamin D.sub.3 and a stabilizer selected from polyvinylacetal diethylaminoacetate and hydroxypropylcellulose. Also disclosed are processes for the preparation of stable dosage-form active vitamins D.sub.3. Each process comprises adding the above stabilizer to an active vitamin D.sub.3 and then adding a pharmaceutically-acceptable carrier to the resultant mixture.

REFERENCES:
patent: 1819297 (1933-07-01), Kropp et al.
patent: 3089822 (1963-05-01), Schenk
patent: 3823237 (1974-07-01), Frank
patent: 4012509 (1977-03-01), Frank
patent: 4308264 (1981-12-01), Conway et al.
patent: 4729895 (1988-03-01), Makino et al.
patent: 4948788 (1990-08-01), Makino et al.

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