Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1975-04-29
1978-09-12
Padgett, Benjamin R.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
424 15, 424 9, A61K 2900, A61K 4300
Patent
active
041138503
ABSTRACT:
The present invention relates to an injectable complex used for the diagnostic visualization of neoplastic tissues i.e., tumors and metastases, by means of tissue scintigraphy, said injectable complex consisting essentially of .sup.99m Technetium with a dicarboxylic or tricarboxylic acid of the general formula: ##STR1## in which n is 1 or 2, R.sup.1 and R.sup.2 taken together are an oxo group or a >CH--COOH group or R.sup.1 is hydrogen or hydroxyl or an amino group and R.sup.2 is hydrogen or one of the following groups:
REFERENCES:
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Sarin et al, Journal of Inorganic and Nuclear Chemistry, vol. 34, No. 1, Jan., 1972, pp. 581-590.
Ando et al, Nuclear Science Abstracts, vol. 29, No. 10, May 31, 1974, p. 2366, abstract No. 24540.
Markovits et al, Inorganic Chemistry, vol. 11, No. 10, Oct. 1972, pp. 2405-2408.
Zeidler et al, Nuclear Science Abstracts, vol. 29, No. 8, Apr. 30, 1974, p. 1812, abstract No. 18716.
Schneider, Journal of Nuclear Medicine, vol. 14, No. 11, Nov. 1973, pp. 843-845.
Nucker Christine M.
Padgett Benjamin R.
Solco Basel AG
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