Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1991-06-06
1992-12-15
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
264 41, 436547, 436548, 436829, 514 2, 514 8, 514 21, 530402, 530812, 5303911, A61K 3722, A61K 3100, A61K 3710
Patent
active
051715783
ABSTRACT:
The present invention describes a composition consisting of liposomes covalently or non-covalently coupled to the glycoprotein streptavidin. The streptavidin may additionally be coupled to biotinated proteins such as Immunoglobulin G or monoclonal antibodies.
The liposomes of the invention may have a transmembrane potential across their membranes, and may be dehydrated. In addition, the composition may contain ionizable bioactive agents such as antineoplastic agents, and may be used in diagnostic assays.
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Bally Marcel B.
Cullis Pieter R.
Loughrey Helen
Bloom Allen
Gowen Catherine Kurtz
Kishore G. S.
Page Thurman K.
The Liposome Company Inc.
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