Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-09-30
1999-08-10
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514451, 514457, A61K 3135
Patent
active
059359960
ABSTRACT:
It is an object of this invention to provide a composition capable of being used for foods and pharmaceuticals, which stimulates osteogenesis and has an effect for preventing reduction of a bone salt content, and which is useful for therapy and prevention of osteoporosis, fracture and the like.
The composition is characterized by containing an isoflavone as a main active ingredient. The composition be preferably ingested so that the concentration of genistein in blood in one hour after ingestion is 10.sup.-7 M or more. Further preferably, the composition contains zinc salt whose concentration in blood is 10.sup.-7 M or more.
REFERENCES:
patent: 5506211 (1996-04-01), Barnes et al.
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"Zinc Stimulation of Bone Protein Synthesis in Tissue Culture--Activation of Aminoacyl-tRNA Synthetase", Yamaguchi et al, Biochemical Pharmacology, vol. 37, No. 21, 1988, pp. 4075-4080.
"Effect of Vitamin K.sub.2 (menaquinone-7) on Bone Metabolism in the Femoral-Metaphyseal Tissues of Normal and Skeletal-Unloaded Rates: Enhancement with Zinc", Ehara e al, Research In Experimental Medicine, 1996, pp. 196:171-178.
Criares Theodore J.
Taishi Foods Company Ltd.
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