Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice
Patent
1994-06-06
1997-01-28
Spear, James M.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Cosmetic, antiperspirant, dentifrice
424450, 424490, 424489, 514770, 514880, 514937, 514952, 514975, 514167, A61K 706, A61K 910, A61K 914, A61K 918
Patent
active
055975755
ABSTRACT:
This application proposes a new topical treatment for the stimulation and induction of hair growth as well as for preventing further hair loss. These pharmacologic results would be achieved by stimulation of an inactive hair follicle or by reversing the dysfunction of the hair follicles or by improvement of the general physiologic state of the scalp skin. It would also stimulate the maturation and differentiation of those cells specifically involved in hair growth either directly or by stimulating the organelles and supporting structures associated with the hair follicle. The topical composition comprises vitamin D.sub.3 or various nitro-benzoic acids esters thereof, or the biologically active metabolites of vitamin D.sub.3 preferabiy affixed, during preparation to microparticulate charged non-metaliic microparticles and aloe. The final concentration of vitamin D.sub.3 in the composition is 0.5% or 500,000 IU by volume. To this composition other agents, vitamins, aminoacids, trace elements or minerals, or polysaccharides can be added in nontoxic amounts. In a trial of a series of patients treated with the composition all were noted to nave cessation of hair loss followed by hair regrowth.
REFERENCES:
patent: 4897269 (1990-01-01), Mezei
patent: 5183817 (1993-02-01), Bazzano
patent: 5427776 (1995-06-01), Isnard
patent: 5486509 (1996-01-01), Jimenez et al.
Sommer Evelyn M.
Spear James M.
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