Composition for stabilization of diagnostic reagents

Details Composition for stabilization of diagnostic reagents Composition for stabilization of diagnostic reagents

1987-08-27

1989-08-22

Richman, Barry S.

Chemistry: analytical and immunological testing

Composition for standardization, calibration, simulation,...

Protein or peptide standard or control

436 18, 436509, 436510, 436511, G01N 3100

Patent

active

048596043

ABSTRACT:
Disclosed herein is a composition useful for stabilizing diagnostic reagent which functions to react with a specimen to determine the presence or absence of a biological condition comprising about 0.01 to 35 parts by weight protein or peptide and either (A) about 1 to 90 parts by weight of a saccharide polyol selected from the group consisting of corn syrup and dextrose and optionally up to about 25 parts by weight of a pyrrol, or (B) about 1 to 90 parts by weight of a saccharide polyol and about 0.01 to 25 parts by weight of a pyrrol. Also disclosed is a method of stabilizing such diagnostic reagents comprising using the stabilizing composition, and a diagnositc device comprising a non-absorbent base carrying at least one deposition area in which is carried the evaporative residue of such diagnostic reagent and the stabilizing composition.

REFERENCES:
patent: 3666421 (1972-05-01), Price
patent: 3770383 (1973-11-01), Price
patent: 3920580 (1975-11-01), Mast
patent: 4121905 (1978-10-01), Maurukas
patent: 4189401 (1980-02-01), Louderback
patent: 4379847 (1983-04-01), Fruitstone et al.
patent: 4578282 (1986-03-01), Harrison

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