Composition for solid pharmaceutical preparations of active vita

Details Composition for solid pharmaceutical preparations of active vita Composition for solid pharmaceutical preparations of active vita

1987-03-16

1988-03-08

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424493, 424494, 424495, 424497, 514167, 514960, A61K 920, A61K 926

Patent

active

047298952

ABSTRACT:
This invention is concerned with a composition for solid pharmaceutical preparations of active vitamins D.sub.3, having the remarkably improved stability of active vitamins D.sub.3, and an extremely advantageous process for the preparation thereof from the industrial viewpoint. The composition of this invention is a composition for solid pharmaceutical preparations of active vitamins D.sub.3 prepared by forming an outer layer comprising active vitamins D.sub.3 and an excipient, which is readily soluble in an organic solvent, around an inner layer comprising an excipient which is slightly soluble in an organic solvent.

REFERENCES:
patent: 2691619 (1954-10-01), Bavley et al.
patent: 3932615 (1976-01-01), Ito et al.
patent: 3957966 (1976-05-01), Valan
patent: 4016254 (1977-04-01), Seager
patent: 4341759 (1982-07-01), Bogentoft et al.

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