Composition for skin patch preparation and process for preparing

Details Composition for skin patch preparation and process for preparing Composition for skin patch preparation and process for preparing

1998-02-18

2000-03-21

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

525363, A61K 970, A61L 560

Patent

active

060399716

ABSTRACT:
A composition for a skin patch including a synthetic polymer gel prepared by reacting a water-soluble polymer of an aliphatic carboxylic acid or a salt thereof with a sparingly soluble aluminum compound, an organic acid containing a hydroxyl group in its molecule as a reaction accelerator, and an ethylenediamine compound as a reaction inhibitor in the presence of water at a pH of 4.0 to 6.1. The composition can homogeneously gel at any crosslinking rate and does not cause any change in quality with the lapse of time.

REFERENCES:
patent: 3839255 (1974-10-01), Podlas
patent: 5116621 (1992-05-01), Oji et al.
Kusunoki et al, Physicochemical Reaction Characteristics of Patches Comprising Aluminum-Crosslinked Gel of Partially Neutralized Polyacrylic Acid, The Abstracts of the 117th Annual Meeting of Pharmaceutical Society of Japan, 27[G3]15-1, Mar. 5, 1997 and English language translation.

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