Composition for sealing and healing wounds

Surgery – Means and methods for collecting body fluids or waste material – Absorbent pad for external or internal application and...

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604304, 128156, A61K 3702

Patent

active

044539398

ABSTRACT:
A composition and its use for sealing and healing of wounds, comprising a collagen carrier which is coated on one face or all faces with a mixture of (1) a fibrinogen component which contains fibrinogen, factor XIII-containing fibrinogen or a mixture thereof, and (2) a thrombin component which contains thrombin, a substance which liberates thrombin in the presence of body fluid or a mixture of such substances. The mixture of (1) and (2) optionally may additionally contain conventional additives, such as calcium ions, protease inhibitors, heparin antagonists, substances which promote the infiltration and growth of fibroblasts, such as fibronectin, as well as antibiotics and/or bactericides.

REFERENCES:
patent: 4265233 (1981-05-01), Sugitachi et al.
Wiener Medizinische Wochenschrift 7, 86 to 89 (1976).

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