Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1998-02-26
2000-04-04
Kulkosky, Peter F.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
514900, 514902, A61K 726
Patent
active
060458003
ABSTRACT:
The present invention provides a composition for preventing or treating periodontal diseases comprising an extract of Achyranthis radix, Ulmus cortex or a mixture thereof which inhibits the productions of superoxide, prostaglandin, and interleukin (IL-1.beta.) which are inducers for periodontal diseases and inhibits the enzyme activity of collagenase which decomposes collagen protein which is a substrate for the periodontal tissues, and at the same time promotes collagen protein synthesis, thereby treating periodontal diseases efficiently.
REFERENCES:
patent: 5230895 (1993-07-01), Czarnecki et al.
CA: 1996:69673 Lee et al "The Influence of Methanol Extract of Ulmus davidiana . . . " 1995.
BA 94:12460 Pan et al Shoyakugaku Zasshi (1992) 46(2), 131-135.
CA: 96:523 Girach et al Int. J. Pharmacog. (1994) 32(3) 274-283.
CA 92:50252 Forestieri et al Pharm. Res. Commun. Suppl. (1988) 20(5) 33-36.
Choi Kyung Chul
Kim Moon Moo
Kim Sang Nyun
Seok Jae Kyun
Kulkosky Peter F.
LG Chemical Ltd.
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