Surgery – Means for introducing or removing material from body for... – With means for cutting – scarifying – or vibrating tissue
Patent
1990-02-23
1992-01-14
Pellegrino, Stephen C.
Surgery
Means for introducing or removing material from body for...
With means for cutting, scarifying, or vibrating tissue
604 27, 604 49, A61B 1720
Patent
active
050806475
ABSTRACT:
The present invention relates to compositions for killing undifferentiated epithelial cells during cataract surgery on an eye to prevent posterior capsule clouding after the surgery and to a method for performing cataract surgery on an eye including injecting a cell-killing substance between the anterior capsule and the natural lens prior to removing the natural lens from the eye. The cell-killing substance is preferably an acid or base adjusted aqueous solution having a pH in the range between about 1.0 to below 6.5 or about above 7.5 to 14.0; or a hypotonic solution having a salinity less than 0.9% or a pH adjusted hypotonic solution having a salinity less than 0.9% and a pH either below 6.5 or above 7.5. The compositions of the present invention also incorporates a viscoelastic material, a dye or a mixture thereof, in combination with the cell-killing substance.
REFERENCES:
patent: 4191176 (1980-03-01), Spina et al.
patent: 4650461 (1987-03-01), Woods
patent: 4871350 (1989-10-01), Lam et al.
patent: 4965253 (1990-10-01), Goldberg et al.
patent: 4966577 (1990-10-01), Crosson et al.
Pellegrino Stephen C.
Rafa Michael
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