Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1991-10-09
1993-12-28
Michl, Paul R.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 514912, 604 22, 604 27, 604 28, 604 30, 604 31, 604 35, 604 36, 604 38, 604 39, 604 40, 604 41, 604 42, 604 43, 604 45, 604 48, 604 49, A61F 214, A01N 2504, A61M 100
Patent
active
052737519
ABSTRACT:
The present invention relates to compositions for killing undifferentiated epithelial cells during cataract surgery on an eye to prevent posterior capsule clouding after the surgery and to a method for performing cataract surgery on an eye including injecting a cell-killing substance between the anterior capsule and the natural lens prior to removing the natural lens from the eye. The cell-killing substance is preferably an acid or base adjusted aqueous solution having a pH in the range between about 1.0 to below 6.5 or about above 7.5 to 14.0; or a hypotonic solution having a salinity less than 0.9% or a pH adjusted hypotonic solution having a salinity less than 0.9% and a pH either below 6.5 or above 7.5. The compositions of the present invention also incorporates a viscoelastic material, a dye or a mixture thereof, in combination with the cell-killing substance.
REFERENCES:
patent: 4819617 (1989-04-01), Goldberg et al.
patent: 4909784 (1990-03-01), Dubroff
patent: 4965253 (1990-10-01), Goldberg et al.
patent: 5013295 (1991-05-01), Dubroff
Azpuru Carlos
Michl Paul R.
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