Composition for preservation of diagnostic test reagents

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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252380, 252401, 252405, 252406, 435810, 435963, 435967, 435975, 436 8, 436 18, 436176, 436808, 436826, G01N 3353

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active

053004248

ABSTRACT:
The present invention is concerned with a combination for the preservation of diagnostic tests, characterized by a content of at least two components selected from the group comprising 2-methyl-4-isothiazolin-3-one hydrochloride, 2-hydroxypyridine-N-oxide, chloroacetamide, (N,N-methylene-bis-(N-(1-hydroxymethyl-2,5-dioxo-4-imidazolidinyl))-urea and 5-bromo-5-nitro-1,3-dioxan.
The present invention is also concerned with a preserved diagnostic test kit, comprising test reagents and at least two preservation agents selected from the group comprising 2-methyl-4-isothiazolin-3-one hydrochloride, 2-hydroxypyridine-N-oxide, chloroacetamide, (N,N-methylene-bis-(N-(1-hydroxymethyl)-2,5-dioxo-4-imidazolidinyl))-urea and 5-bromo-5-nitro-1,3-dioxan.

REFERENCES:
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patent: 4868139 (1989-09-01), Deeg et al.
patent: 4966838 (1990-10-01), Ferrua et al.
Chemical Abstracts (1988) vol. 108, No. 21, p. 378.
Rosen, W. E., et al. (1984) Cosmet. Sci. Technol. pp. 191-205.
Ghannoum, M., et al. (1986) Folin Microbiol. 31:19-31.

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