Composition for patient sample preparation

Compositions – Nonreactive analytical – testing – or indicating compositions

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436 18, 436176, G01N 3100

Patent

active

059583002

ABSTRACT:
The object of the present invention is to claim a composition which when added to a patient sample containing a target antigen in an acidic or formalin-containing transport medium neutralizes the acid and formalin while preserving immunoreactivity of the antigen allowing its detection. The composition comprises an amino glycol buffer, an amino acid, a salt, and a non-ionic detergent. A further object of the present invention is to claim a method of processing a sample by adding a composition comprising an amino glycol buffer, an amino acid, a salt, and a non-ionic detergent.

REFERENCES:
patent: 4260599 (1981-04-01), Okazaki et al.
patent: 4948726 (1990-08-01), Longoria
patent: 5164485 (1992-11-01), Yukio et al.
patent: 5212297 (1993-05-01), Colella et al.
patent: 5328913 (1994-07-01), Murad et al.
patent: 5593859 (1997-01-01), Prockop et al.

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