Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1998-01-28
1999-08-24
Harrison, Robert H.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424464, 5142365, 514960, 514970, A61K 3153, A61K 920
Patent
active
059422491
ABSTRACT:
A composition for oral administration which contains a pyridazinone compound of the formula (I) ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are each independently a hydrogen atom or a lower alkyl, X is a halogen atom, a cyano or a hydrogen atom, Y is a halogen atom, a trifluoromethyl or a hydrogen atom, and A is a C.sub.1 -C.sub.8 alkylene optionally substituted by hydroxy, or a pharmacologically acceptable salt thereof, and an organic acid. According to the present invention, a composition for oral administration which is stable to heat, light, moisture and the like and which shows improved dissolution and absorption of a pyridazinone compound can be provided.
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patent: 5202323 (1993-04-01), Tanikawa et al.
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patent: 5364646 (1994-11-01), Gruber et al.
patent: 5424075 (1995-06-01), Daher et al.
Iwao Toru
Kondo Nobuo
Seki Tomoyo
Ueda Yasuo
Harrison Robert H.
Nissan Chemical Industries Ltd.
The Green Cross Corporation
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