Composition for long-acting peptide analogs

Details Composition for long-acting peptide analogs Composition for long-acting peptide analogs

2011-06-14

2011-06-14

Russel, Jeffrey (Department: 1654)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S010900, C514S015600, C530S315000, C530S345000

Reexamination Certificate

active

07960336

ABSTRACT:
The invention describes compositions of peptide analogs exemplified by peptides derived from vasopressin, terlipressin, and GLP1 and others that are active in blood or cleavable in blood to release an active peptide. The peptide analogs have a general formula: A-(Cm)x-Peptide, wherein A is a hydrophobic moiety or a metal binding moiety, and Cm is a cleavable moiety consisting of glycine or alanine or lysine or arginine or N-Arginine or N-lysine, wherein x is an integer between 0-6 and N may be any amino acid or none. A may be linked to Cm by a linker group. The peptide analogs are complexed with polymeric carrier to provide enhanced half-life.

REFERENCES:
patent: 3998795 (1976-12-01), Sarantakis
patent: 4857311 (1989-08-01), Domb et al.
patent: 5019383 (1991-05-01), Hopp
patent: 5118666 (1992-06-01), Habener
patent: 5120712 (1992-06-01), Habener
patent: 5527524 (1996-06-01), Tomalia et al.
patent: 5554388 (1996-09-01), Illum
patent: 5593658 (1997-01-01), Bogdanov et al.
patent: 5605672 (1997-02-01), Bogdanov et al.
patent: 5614492 (1997-03-01), Habener
patent: 5631018 (1997-05-01), Zalipsky et al.
patent: 5661025 (1997-08-01), Szoka, Jr. et al.
patent: 5663387 (1997-09-01), Singh
patent: 5681544 (1997-10-01), Schmitt-Willich et al.
patent: 5714166 (1998-02-01), Tomalia et al.
patent: 5744166 (1998-04-01), Illum
patent: 5763585 (1998-06-01), Nag
patent: 5837747 (1998-11-01), Soon-Shiong et al.
patent: 5871710 (1999-02-01), Bogdanov et al.
patent: 5891418 (1999-04-01), Sharma
patent: 5958909 (1999-09-01), Habener
patent: 5977084 (1999-11-01), Szoka, Jr. et al.
patent: 5990273 (1999-11-01), Andersson et al.
patent: 6006753 (1999-12-01), Efendic
patent: 6051549 (2000-04-01), Roberts et al.
patent: 6113946 (2000-09-01), Szoka, Jr. et al.
patent: 6124273 (2000-09-01), Drohan et al.
patent: 6162462 (2000-12-01), Bolotin et al.
patent: 6177274 (2001-01-01), Park et al.
patent: 6232366 (2001-05-01), Wang et al.
patent: 6274175 (2001-08-01), Gombotz et al.
patent: 6284727 (2001-09-01), Kim et al.
patent: 6338859 (2002-01-01), Leroux et al.
patent: 6348069 (2002-02-01), Vacanti et al.
patent: 6365173 (2002-04-01), Domb et al.
patent: 6395299 (2002-05-01), Babich et al.
patent: 6443898 (2002-09-01), Unger et al.
patent: 6447753 (2002-09-01), Edwards et al.
patent: 6458373 (2002-10-01), Lambert et al.
patent: 6468532 (2002-10-01), Hsei et al.
patent: 6475779 (2002-11-01), Mathiowitz et al.
patent: 6492560 (2002-12-01), Wilbur et al.
patent: 6509323 (2003-01-01), Davis et al.
patent: 6521211 (2003-02-01), Unger et al.
patent: 6521736 (2003-02-01), Watterson et al.
patent: 6576254 (2003-06-01), Uchegbu
patent: 6579851 (2003-06-01), Goeke et al.
patent: 6583111 (2003-06-01), DiMarchi et al.
patent: 6586524 (2003-07-01), Sagara
patent: 6589549 (2003-07-01), Shih et al.
patent: 6627228 (2003-09-01), Milstein et al.
patent: 6703037 (2004-03-01), Hubbell et al.
patent: 6703359 (2004-03-01), Young et al.
patent: 6706689 (2004-03-01), Coolidge et al.
patent: 6747006 (2004-06-01), Efendic
patent: 6828303 (2004-12-01), Kim et al.
patent: 6849708 (2005-02-01), Habener
patent: 6884628 (2005-04-01), Hubbell et al.
patent: 6894024 (2005-05-01), Coolidge et al.
patent: 6899883 (2005-05-01), Dupre
patent: 6982248 (2006-01-01), Coolidge et al.
patent: 6992060 (2006-01-01), Brand
patent: 6998137 (2006-02-01), Shih et al.
patent: 7049284 (2006-05-01), Drucker
patent: 7101843 (2006-09-01), Glaesner et al.
patent: 7138105 (2006-11-01), Bolotin
patent: 7138486 (2006-11-01), Habener et al.
patent: 7144863 (2006-12-01), DeFelippis et al.
patent: 7199217 (2007-04-01), DiMarchi et al.
patent: 7259233 (2007-08-01), Dodd et al.
patent: 7319000 (2008-01-01), Sastry et al.
patent: 7534449 (2009-05-01), Saltzman et al.
patent: 2001/0006817 (2001-07-01), Pack et al.
patent: 2002/0015737 (2002-02-01), Shih et al.
patent: 2002/0132254 (2002-09-01), Twu
patent: 2003/0050237 (2003-03-01), Kim et al.
patent: 2003/0119734 (2003-06-01), Flink et al.
patent: 2003/0138407 (2003-07-01), Lu et al.
patent: 2003/0220251 (2003-11-01), Knudsen et al.
patent: 2003/0224974 (2003-12-01), Bolotin
patent: 2003/0229034 (2003-12-01), Waugh et al.
patent: 2003/0232968 (2003-12-01), Li et al.
patent: 2004/0018176 (2004-01-01), Tolentino et al.
patent: 2004/0077840 (2004-04-01), Granoff et al.
patent: 2004/0092432 (2004-05-01), During et al.
patent: 2004/0106589 (2004-06-01), Webb et al.
patent: 2004/0162241 (2004-08-01), Efendic
patent: 2004/0197369 (2004-10-01), Hubbell et al.
patent: 2004/0209803 (2004-10-01), Baron et al.
patent: 2004/0220105 (2004-11-01), Jensen et al.
patent: 2004/0235726 (2004-11-01), Jakubowski et al.
patent: 2004/0266683 (2004-12-01), Hathaway et al.
patent: 2005/0008661 (2005-01-01), Fereira et al.
patent: 2005/0014681 (2005-01-01), Minamitake et al.
patent: 2005/0037075 (2005-02-01), Farokhzad et al.
patent: 2005/0143303 (2005-06-01), Quay et al.
patent: 2005/0148497 (2005-07-01), Khan
patent: 2005/0153913 (2005-07-01), Kosak
patent: 2005/0159356 (2005-07-01), Dong et al.
patent: 2005/0215475 (2005-09-01), Ong et al.
patent: 2005/0239705 (2005-10-01), Dake et al.
patent: 2005/0260259 (2005-11-01), Bolotin
patent: 2006/0003935 (2006-01-01), Pan et al.
patent: 2006/0014695 (2006-01-01), Ghandehari et al.
patent: 2006/0019874 (2006-01-01), Radhakrishnan et al.
patent: 2006/0030838 (2006-02-01), Gonnelli
patent: 2006/0035815 (2006-02-01), Chen et al.
patent: 2006/0040879 (2006-02-01), Kosak
patent: 2006/0057137 (2006-03-01), Steiness
patent: 2006/0074025 (2006-04-01), Quay et al.
patent: 2006/0093660 (2006-05-01), Bolotin
patent: 2006/0128627 (2006-06-01), Goke et al.
patent: 2006/0172001 (2006-08-01), Ong et al.
patent: 2006/0172003 (2006-08-01), Meers et al.
patent: 2006/0178304 (2006-08-01), Juul-Mortensen et al.
patent: 2006/0183682 (2006-08-01), Juul-Mortensen
patent: 2006/0199763 (2006-09-01), Knudsen et al.
patent: 2006/0233857 (2006-10-01), Amsden et al.
patent: 2006/0239924 (2006-10-01), Bolotin
patent: 2006/0247167 (2006-11-01), Schlein et al.
patent: 2006/0286129 (2006-12-01), Sarubbi
patent: 2007/0036806 (2007-02-01), Glaesner et al.
patent: 2007/0041951 (2007-02-01), Egan et al.
patent: 2007/0141006 (2007-06-01), Livoreil et al.
patent: 2007/0141145 (2007-06-01), Castillo et al.
patent: 2007/0219118 (2007-09-01), Lu et al.
patent: 2007/0225213 (2007-09-01), Kosak
patent: 2007/0244296 (2007-10-01), Tomalia et al.
patent: 2007/0298006 (2007-12-01), Tomalia et al.
patent: 2008/0015263 (2008-01-01), Bolotin et al.
patent: 2008/0026995 (2008-01-01), Tosi et al.
patent: 2008/0159992 (2008-07-01), Rotman et al.
patent: 2008/0312174 (2008-12-01), Yu et al.
patent: 2009/0053169 (2009-02-01), Castillo et al.
patent: 2009/0156459 (2009-06-01), Castillo et al.
patent: 0381446 (1994-08-01), None
patent: 10158195 (1998-06-01), None
patent: WO 94/05203 (1994-03-01), None
patent: WO 97/33552 (1997-09-01), None
patent: WO 98/42383 (1998-10-01), None
patent: WO 01/28569 (2001-04-01), None
patent: WO 01/39815 (2001-06-01), None
patent: WO 01/39815 (2002-01-01), None
patent: WO 2002/024213 (2002-03-01), None
patent: WO 2002/024213 (2002-06-01), None
patent: WO 03070749 (2003-08-01), None
patent: WO 03/072143 (2003-09-01), None
patent: WO 2004/014451 (2004-02-01), None
patent: WO 2004/022004 (2004-03-01), None
patent: WO 03/070749 (2004-04-01), None
patent: WO 2004/022004 (2004-12-01), None
patent: WO 2005/076998 (2005-08-01), None
patent: WO 2005/084180 (2005-09-01), None
patent: WO 2005/084180 (2005-12-01), None
patent: WO 2005/076998 (2006-01-01), None
patent: WO 2006/062398 (2006-06-01), None
patent: WO 2006/062398 (2006-10-01), None
patent: WO 2007/024899 (2007-03-01), None
patent: WO 2007/030706 (2007-03-01), None
patent: WO 2007/048190 (2007-05-01), None
patent: WO 2007/056681 (2007-05-01), None
patent: WO 2007/082331 (2007-07-01), None
patent: WO 2007/024899 (2007-11-01), None
patent: WO 2007/056681 (2008-04-01), None
Paramonov et al. Self-Assembly of Peptide-Amphiphile Nanofibers: The Roles of Hydrogen Bonding and Amphiphilic Packing. Journal of the American Chemical Society. 2006, vol. 128, No. 22, pp. 7291-7298.
O'Brie

Affiliated with

Also associated with

Rating

Composition for long-acting peptide analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Composition for long-acting peptide analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition for long-acting peptide analogs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2638793