Composition for enhancing the administration of pharmacologicall

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514270, 514425, 514613, 514722, 514757, 514941, 514943, 514939, A61K 3102, A61K 3108, A61K 3116, A61K 3140

Patent

active

RE0323934

ABSTRACT:
According to the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.

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patent: 3240670 (1966-03-01), Feinberg
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Rote Liste, 1967, p. 780.

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