Composition for enhancing the administration of pharmacologicall

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424254, 424258, 424263, 424273P, 424310, 424330, 424339, 424350, 424358, 61K 3144, A61K 3102, A61K 3133, A61K 3147, A61K 31075, A61K 31135, A61K 31245, A61K 31415, A61K 31515

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active

041683080

ABSTRACT:
According to the invention, the parenteral administration of water-insoluble pharmacologically active agents is enhanced wherein the agents are administered in the lipoid phase of a carrier emulsion comprising a microemulsion of a finely dispersed lipoid in an aqueous phase. The lipoid preferably has a mean particle size below 1 micron. This makes it possible to administer water-insoluble agents in high concentrations, and thus a lower dose, whereby a rapid onset of the pharmacological effect is accompanied by a markedly reduced incidence of injury to body tissues.

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patent: 2867565 (1959-01-01), Feinstone
patent: 2972565 (1961-02-01), Zilversmit
patent: 2988484 (1961-06-01), Barsky
patent: 3089823 (1963-05-01), Czarnecki
patent: 3169094 (1965-02-01), Wretlind
patent: 3216897 (1965-11-01), Krantz et al.
patent: 3240670 (1966-03-01), Feinberg
patent: 3384545 (1968-05-01), Aiello et al.

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