Composition for enhancing drug permeation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514 63, 514398, 514772, 514947, A61K 3144, A61K 31415

Patent

active

052329356

ABSTRACT:
A method of accelerating the permeation of drugs in topical and transdermal delivery of a drug in which a drug is applied to the skin in combination with organosilicon compounds which are carboxyalkyl functional polysiloxanes and alkylsulphoxide functional polysiloxanes. The organosilicon compound may be applied to the skin neat or in the form of a solvent solution containing the organosilicon compound.

REFERENCES:
patent: 5021405 (1991-06-01), Klimisch
Chemical Abstracts 101:157725s (1984).
Chemical Abstracts 110:28918u (1989).

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