Composition for detection of peritoneal inflammation or infectio

Details Composition for detection of peritoneal inflammation or infectio Composition for detection of peritoneal inflammation or infectio

1986-10-22

1988-01-05

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 14, 435 15, 435 18, 435 19, 435 21, 435 23, 435 24, 435 25, 435 26, 435 28, 436 17, C12Q 100, C12Q 300

Patent

active

047176520

ABSTRACT:
Peritoneal inflammation or infection can be detected in a patient by assaying a peritoneal lavage sample from the patient for lysosomal enzymes. This is done by combining the lavage sample with a leukocyte lysing agent and a chromogenic or fluorogenic enzyme substrate specific for lysosomal enzymes. The lysosomal enzymes can then be measured, and the inflammation of infection detected, by measuring the color or fluorescence developed in the sample by action of the enzymes on the substrate.

REFERENCES:
patent: 4528274 (1985-07-01), Carter et al.
Berger et al-Chem. Abst., vol. 93 (1980), p. 65418g.
Berger et al-Chem. Abst., vol. 94 (1981), p. 43719z.
Flegler-Chem. Abst., vol. 101 (1984), pp. 226, 327c.

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