Composition for assaying cardiac glycosides from serum or plasma

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

436 93, 436 94, 436131, 436172, 436174, 436161, 422 70, 2101982, 73 611C, 514 26, A61K 3170, C07J 1900

Patent

active

047646012

ABSTRACT:
A fluorescent compound is made from the reaction of naphthoyl chloride and a cardiac glycoside derived from serum or plasma. The method of carrying out the reaction provides a product which allows for a 100-fold increase in sensitivity when the product is subjected to chromatographic analysis according to the described apparatus.

REFERENCES:
patent: 4184037 (1980-01-01), Wilkinson
patent: 4555504 (1985-11-01), Jones
Abstract Assay of Digoxin and Metabolites in Urine and Feces by HPLC of Fluorescent Derivatives, Theresa Shepard and Richard H. Reuning, College of Pharmacy, OSU, Columbus, OH 43210, p. 647, World Conference on Clinical Pharmocology Therapeutics, Washington, D.C., Jul. 31-Aug. 5, 1983.
I. Methods for Digoxin and Metabolite Determination in Urine, Feces and Plasma and Application to Detection of R-Dihydrodigoxin in Humans and II. A Theroretical Examination of the Kinetics of Enterohepatic Cycling, by Theresa A. Shepard, Ph.D. The Ohio State University, 1983 Professor Richard H. Reuning, Advisor.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Composition for assaying cardiac glycosides from serum or plasma does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Composition for assaying cardiac glycosides from serum or plasma, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Composition for assaying cardiac glycosides from serum or plasma will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-601305

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.