Composition containing platelet factor 4 and method for restorin

Details Composition containing platelet factor 4 and method for restorin Composition containing platelet factor 4 and method for restorin

1985-11-01

1987-10-27

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 85, 424101, 514 8, 514 21, 530300, 530322, 530380, A61K 3514

Patent

active

047029080

ABSTRACT:
Compositions and methods for modulating immune responses in a mammal comprising immunomodulating-effective amounts of platelet factor 4 are disclosed herein. Immunomodulation includes one or more aspects of restoration of suppressed immune responses, inhibition of immune suppression (due to exposure of a mammal of an agent that causes suppressor cell activation) and augmentation of normal immune response.

REFERENCES:
patent: 4350687 (1982-09-01), Lipton et al.
patent: 4479896 (1984-10-01), Antoniades
patent: 4618494 (1986-10-01), Angers
J. Exp. Med. 150:108-116(1979), Hammerling et al.
Blood, 53:47-62(1979), Rucinski et al.
J. Natl. Canc. Inst. 72:125-132, Katz et al (1984).
Biochim. Biophys. Acta 839:161-173(1985), Capitanio et al.

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