Composition containing fine particles for supporting...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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C424S401000, C424S070140

Reexamination Certificate

active

07897176

ABSTRACT:
Provided are a dispersion comprising organic-inorganic hybrid type particles carried thereon with a biologically active substance, wherein the above particles can be obtained by allowing a block copolymer represented by Formula (I):in-line-formulae description="In-line Formulae" end="lead"?PEG-block-poly(carbo)  (I)in-line-formulae description="In-line Formulae" end="tail"?(wherein PEG represents a polyethylene glycol segment, and carbo represents a repetitive unit having a carboxylate ion on a side chain) and an aqueous medium system capable of forming hydroxyapatite to coexist with the biologically active substance, and a preparing method for the same.

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Helmut Cölfen, “Double-Hydrophilic Block Copolymers: Synthesis and Application as Novel Surfactants and Crystal Growth Modifiers”, Macromol. Rapid Commun., vol. 22, pp. 219-252, 2001.

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