Composition containing cordiodilatin or fragments thereof and me

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 14, 514 15, 514 16, 514 17, 530324, 530327, 530328, 530329, A61K 3702

Patent

active

047820446

ABSTRACT:
This invention teaches therapeutic compositions containing the hormone cardiodilatin of active fragments thereof, as well as methods for obtaining the cardiodilatin. The compositions are useful in relaxing smooth, blood vessel muscles.

REFERENCES:
patent: 4604234 (1986-08-01), Fujii et al.
patent: 4638050 (1987-01-01), Aoki et al.
patent: 4675382 (1987-06-01), Murphey
Lazure et al., FEBS Letters, vol. 172, No. 1, pp. 80-86, "Atrial Pronatrilatin: A Precursor for Natriuretic Factor and Cardiodilatin".
Nakayama et al, Nature, vol. 310, No. 3979, pp. 699-701, "m-RNA Sequence for Human Cardiodilatin-Atrial Natriuretic Factor Precursor and Regulation of Precursor m-RNA in Rat Atria".
Forssman et al, "The Right Auricle of the Heart is an Endocrine Organ", Anatomy and Embryology, vol. 168, 307-313, 1983.

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