Composition containing buf-3 and superoxide dismutase as a cell

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

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530399, 530350, 514 12, 424 944, C12N 902, C07K 1300, A61K 3736

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active

052061604

ABSTRACT:
A cleavage promoting agent comprising as an effective ingredient at least one of the polypeptides BUF-3, BUF-4 and BUF-5 is useful for the treatment of fertilized or unfertilized ova in order to promote cell division and improve reproduction efficiency.

REFERENCES:
patent: 4798885 (1989-01-01), Mason et al.
patent: 4997815 (1991-03-01), Perrine et al.
Linn, Stuart. (1989) Methods in Enzymology, vol. 182, p. 11.
Effect of EDTA on in vitro development of ddY mouse eggs fertilized in vitro, Miyake, N. et al. (1987) Kobe Daigaku Nogakubu Kenkyu Hokoku 17(2) 245-250.
Japanese Journal of Animal Reproduction vol. 36, No. 2, Jun. 1990, pp. 127-133; Rong-zhen, Lu et al: "Activin A (EDF) releases the `two cell block` of mouse embryos in culture".
Roxus Archives of Developmental Biology vol. 198, 1990, pp. 330-335; Makoto Asashima et al: "Mesodermal induction in early amphibian embryos by activin A (erythroid diferentiation factor)".

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