Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-03-04
2009-11-03
Chu, Yong (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S254080, C514S323000, C514S414000
Reexamination Certificate
active
07612066
ABSTRACT:
The present invention provides a composition containing a benzamidine derivative that does not decompose even when placed under humidification conditions and a method for stabilizing a benzamidine derivative. According to the present invention, decomposition reaction of a benzamidine derivative can be suppressed by adding to a benzamidine derivative represented by general formula (I) or a pharmacologically acceptable salt thereof, at least one type of electrolyte selected from the group consisting of halide salts of alkaline metal or alkaline earth metal and alkaline metal salts or alkaline earth metal salts of perchloric acid.
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FDA drug Application No. NDA #019437 (Aminosyn II).
Fujioka Satoshi
Suzuki Yasuyuki
Birch & Stewart Kolasch & Birch, LLP
Chu Yong
Eisai R&D Management Co., Ltd.
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