Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1987-07-30
1989-07-04
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Lymphokine
514 8, 514 14, 514 21, 530327, 530380, 424 851, A61K 3514, C07K 708
Patent
active
048448958
ABSTRACT:
Compositions and methods for modulating immune responses in mammals comprising immunomodulating-effective amounts of PF4 or a biologically active peptide fragment of platelet factor 4 are disclosed herein. Immunomodulation includes one or more aspects of restoration of suppressed immune responses, inhibition of immune suppression (due to exposure of a mammal of an agent that causes suppressor cell activation) and augmentation of normal immune responses.
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Thorbecke G. Jeanette
Zucker Marjorie B.
New York University
Schain Howard E.
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