Composition containing a penem or carbapenem antibiotic and the

Details Composition containing a penem or carbapenem antibiotic and the Composition containing a penem or carbapenem antibiotic and the

1986-10-10

1988-07-12

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

424 85, 540350, A61K 3140

Patent

active

047570660

ABSTRACT:
Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially.

REFERENCES:
patent: 4427690 (1984-01-01), Cole et al.
patent: 4536335 (1985-08-01), Kim et al.
patent: 4543257 (1985-09-01), Cama et al.
patent: 4552873 (1985-11-01), Miyadera et al.
patent: 4576939 (1986-03-01), Ross et al.
Cecil Textbook of Medicine, 16th Edition, editor Wyngaarden et al., W. B. Saunders Company, Philadelphia, Pa., 1970, pp. 62-65.
Kagan, Antimicrobial Therapy, W. B. Saunders Company, Philadelphia, Pa., 1970, pp. 68-70 and 170-173.

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