Composition containing a complex of a polyvalent metal and a DNA

Details Composition containing a complex of a polyvalent metal and a DNA Composition containing a complex of a polyvalent metal and a DNA

1997-07-21

1999-12-07

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Urogenital system

424520, 514 44, A61K 3552, A61K 3512, A01N 4304

Patent

active

059979097

ABSTRACT:
Compositions are provided which contain a complex of a polyvalent metal and sodium salt, the DNA-sodium salt being obtained from sturgeon milt. The complexes exhibit high antiviral activity and low toxicity.

REFERENCES:
patent: 5645982 (1997-07-01), Bonyhadi et al.
patent: 5733540 (1998-03-01), Lee
Ng et al. "Anti-human immunodefficiency virus (anti-HIV) natural products with special emphasis on HIV reverse transcriptate inhibitors," Life Sciences (1997) 61(10): 933-949.
Smythe et al. "Gene theraputic agents: The use of ribozymes, antisense, and RNA decoys for HIV-1 infection," Inflamm. Res. (1995) 44: 11-15.
Misson et al. "Theraputic advances: Protease inhibitors for the treatment of HIV-1 infection," J. Clin. Pharmacy Thereaputics (1997) 22: 109-117.

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